TECHNOLOGY BACKGROUND

Bead-based multiplex arrays are commonly used for the detection of various biomarkers and proteins. This technique uses microsphere beads, coated with monoclonal antibodies against specific proteins, to simultaneously measure multiple analyte concentrations in various sample types such as:

• Body fluids (serum, saliva, plasma, GCF, wound fluid, etc)
• Cell and tissue lysates/extracts
• Culture supernatants
• Target species including human, mouse, rat, non-human primate, canine, porcine, etc.

Luminex® and their partners have developed many applications using the XMAP® Technology platform, including the following fields of life science research:

• Cancer Markers
• Cardiovascular
• Cell Signaling
• Cellular Metabolism
• Immunology
• Gene Expression Profiling
• Genotyping
• Endocrinology
• Isotyping
• Matrix
• Metalloproteinases
• Metabolic Endocirnology